Bordering south Georgia in the North Central/Suwannee River Region of Florida, Hamilton County was formed in 1827 from Jefferson County. Its county seat, Jasper, is just off I-75 about 80 miles west of Jacksonville and 80 miles east of Tallahassee. Hamilton is bordered by the Florida counties of Columbia, Suwannee, and Madison, and the Georgia counties of Lowndes and Echols.